Emgality (galcanezumab-gnlm) is a migraine medication that has garnered considerable attention since its approval by the U.S. Food and Drug Administration (FDA) in 2018. Designed to prevent migraine attacks in adults, this injectable treatment is classified as a CGRP (calcitonin gene-related peptide) inhibitor. For those who have been prescribed Emgality, one critical aspect comes to the forefront: its storage requirements. Specifically, does Emgality have to be refrigerated? In this comprehensive article, we will explore Emgality’s storage needs, its efficacy, and essential considerations when using this medication.
What Is Emgality?
Emgality is part of a new class of medications aimed at preventing migraines. It works by blocking the activity of CGRP, a molecule in the brain associated with migraine attacks. By inhibiting this peptide, Emgality significantly reduces both the frequency and severity of migraines.
Importance of Proper Storage
Proper storage of medications is crucial for maintaining their safety and efficacy. Incorrect storage can lead to degradation, which may impair the drug’s effectiveness and may even pose health risks to users. Understanding how to store Emgality properly can ensure that patients receive the full benefits of their treatment.
Does Emgality Need To Be Refrigerated?
The direct answer is yes, Emgality does need to be refrigerated. However, there are specific details that patients should keep in mind regarding its storage:
- Temperature Range: Emgality should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). This temperature range helps maintain the medication’s effectiveness and stability.
- Avoid Freezing: It is crucial to ensure that Emgality does not freeze. Freezing can damage the drug, rendering it ineffective and potentially harmful.
What If I Forget To Refrigerate It?
While the refrigerator is the ideal storage location for Emgality, there may be instances when patients inadvertently leave it out. According to the manufacturer, if Emgality is exposed to room temperature (up to 77°F or 25°C) for a maximum of 7 days, it can still be used, provided it has not been frozen. However, if it has been left out longer than this period, or if it has been frozen, it is recommended to dispose of it and obtain a new supply.
How to Store and Handle Emgality
Storing Emgality takes some precautionary actions that every user should follow to ensure their medication remains effective.
Storage Tips
Here are some important tips for the storage of Emgality:
- Keep Away From Light: Emgality should be stored in its original packaging to protect it from light. Light exposure can potentially degrade the medication.
- Avoid Bathroom Storage: Bathrooms often have fluctuating temperatures and high humidity, which are not ideal for medication storage. A cool, dry place away from direct sunlight would be a better choice.
Preparing for an Injection
When preparing to administer Emgality, users should follow these steps to ensure the medication is handled safely and effectively:
- Remove from Refrigerator: Take Emgality from the fridge and allow it to sit at room temperature for 30 minutes before injecting. This helps improve comfort during the injection.
- Inspect the Solution: Before injecting, inspect the solution for any discoloration or particles. Emgality should be clear and colorless. If you notice any changes, do not use it.
The Importance of Following Storage Guidelines
Adhering to proper storage guidelines is vital for several reasons:
Maintaining Efficacy
Efficacy of the medication can be significantly impacted if it is not stored correctly. Chemicals in the drug might break down if exposed to inappropriate temperatures or conditions, potentially leading to reduced effectiveness during treatment.
Safety Considerations
Safety is paramount when it comes to medication administration. Using a drug that has been improperly stored can introduce risks, including allergic reactions or adverse side effects. In the worst-case scenario, using a compromised drug could lead to a lack of desired therapeutic effects.
What to Do in Case of Improper Storage
If by chance you discover that Emgality was not stored correctly, it is essential to assess the situation with care.
Evaluate the Duration
Consider how long the drug has been out of the refrigerator and whether it may have frozen. If it was only out for a brief, controllable period (less than 7 days) and has not been frozen, it is still safe to use. However, if it has been out too long or has frozen, it should be discarded.
Consult Your Healthcare Provider
If you are uncertain about whether to use Emgality after improper storage, it’s always a good idea to consult with a healthcare provider or pharmacist. They can provide guidance based on your specific situation and help determine whether you need a refill.
Cost and Availability of Emgality
Like many specialty medications, the cost of Emgality can be a concern for patients. It includes not just the price of the medicine itself but also expenses related to storage and proper disposal methods.
Insurance Coverage and Patient Assistance
Many insurance plans cover Emgality, but coverage can vary widely. Patients should check with their insurance provider regarding their specific policies and shared cost responsibilities.
Additionally, the manufacturer offers a patient assistance program to help eligible patients afford their medication. This program can assist with co-pays and even provide the drug at no charge in some cases.
Final Thoughts on Emgality and Storage
In summary, proper storage of Emgality is essential for maintaining its efficacy and safety. Always store it in the refrigerator and follow guidance on handling and preparation. If you are unsure whether your medication is still safe to use after being left out or stored improperly, consult with your healthcare provider.
Emgality is a promising option for many individuals suffering from migraines, and adhering to storage and handling guidelines ensures that patients can maximize its benefits in their treatment plans.
What is Emgality and what is it used for?
Emgality is a medication that contains the active ingredient galcanezumab-gnlm, which is a monoclonal antibody designed for the prevention of migraine in adults. It works by targeting and inhibiting the activity of calcitonin gene-related peptide (CGRP), a molecule that plays a significant role in migraine attacks. Emgality has been clinically proven to reduce the frequency and severity of migraines, providing relief for those who suffer from this debilitating condition.
In addition to migraine prevention, Emgality is also approved for the treatment of episodic cluster headaches. These headaches can occur in cyclical patterns and are known for their intense pain. The efficacy of Emgality in treating both migraines and cluster headaches makes it a valuable option for patients seeking effective management of their headache disorders.
Does Emgality need to be refrigerated?
Yes, Emgality should be stored in a refrigerator at a temperature between 36°F to 46°F (2°C to 8°C). It is important to keep the medication in its original packaging to protect it from light. Refrigerating Emgality helps to maintain its efficacy and stability until it is time for use.
However, if you need to transport Emgality or if refrigeration is temporarily unavailable, it can be stored at room temperature, not exceeding 77°F (25°C), for a maximum of 7 days. It’s crucial to avoid leaving it out longer than this, as it may compromise the medicine’s effectiveness. Always check the expiration date and consult your healthcare provider if you have any concerns about proper storage.
What should I do if Emgality is not refrigerated?
If Emgality has been left out of the refrigerator and you are uncertain about how long it has been at room temperature, it is important to assess the situation carefully. If the medication has been at temperatures exceeding the recommended limit for more than 7 days, it is safer to discard it. Using a medication that may have lost its potency could lead to ineffective treatment.
In instances where Emgality has been out of the fridge for less than 7 days, you can still consider using it as long as it has not been exposed to temperatures above 77°F (25°C). It is best to consult your pharmacist or healthcare provider for guidance on whether the medication is still safe to use. Always err on the side of caution to ensure your health and safety.
Can I freeze Emgality?
No, Emgality should never be frozen. Freezing the medication can alter its chemical structure and effectiveness, potentially rendering it useless. When exposed to freezing temperatures, the formulation can become compromised, which may affect how the drug interacts with the body. Therefore, it is crucial to store Emgality properly to maintain its integrity.
If Emgality has accidentally been frozen, it is important to discard it and not attempt to use it. Always check the integrity of the medication before administration. If you are uncertain about how to store it or worried about a potential mishap, consult your healthcare provider or pharmacist for further instructions.
How should I prepare Emgality for injection?
Before injecting Emgality, it’s essential to let the medication sit at room temperature for about 30 minutes. This allows it to warm up and can help with the injection process, making it more comfortable. Never try to speed up the warming process by using any external heat source. During this time, carefully inspect the medication for discoloration or particulate matter; it should be clear to slightly opalescent and colorless.
Once the product has reached room temperature and has been properly inspected, wash your hands and prepare the injection site, usually on your abdomen or thigh. Follow your healthcare provider’s instructions on the correct technique for self-injection, including the proper disposal of needles. If you have any doubts or questions about how to administer the injection, do not hesitate to reach out to your healthcare provider for assistance.
Are there any side effects associated with Emgality?
Like all medications, Emgality may cause side effects, although not everyone experiences them. Some common side effects include injection site reactions such as pain, redness, or swelling. Other individuals may experience constipation or hypersensitivity reactions. It is essential to monitor how your body responds after you begin treatment and report any concerning symptoms to your healthcare provider promptly.
In rare cases, more serious side effects can occur, such as allergic reactions that may involve symptoms like hives, difficulty breathing, or swelling of the face, lips, or tongue. If you experience any severe reactions after taking Emgality, seek medical attention immediately. Always discuss potential side effects and your specific medical history with your healthcare provider to ensure that Emgality is a safe option for you.