Xeomin is a neurotoxin that is commonly used for cosmetic purposes, such as reducing the appearance of wrinkles and fine lines. It is similar to Botox and Dysport, but there are some differences in its formulation and storage requirements. One common question that arises when it comes to Xeomin is whether it needs to be refrigerated. In this article, we will explore everything you need to know about the storage and refrigeration of Xeomin.
To begin with, let’s understand what Xeomin is and how it works. Xeomin is derived from the bacterium Clostridium botulinum, which produces a toxin called botulinum toxin type A. This toxin acts by temporarily blocking nerve activity in the muscles, leading to a reduction in muscle contractions. By doing so, Xeomin can effectively smooth out wrinkles and lines, providing a more youthful appearance.
How does Xeomin differ from other neurotoxins?
When it comes to neurotoxins used for cosmetic purposes, Botox and Dysport are more commonly known. However, Xeomin has its unique characteristics. Unlike Botox, Xeomin is a “naked” neurotoxin, meaning it does not contain any additional proteins. This purity may have advantages for some patients, as it reduces the likelihood of the immune system developing a resistance to the neurotoxin. Additionally, Xeomin does not require refrigeration at the time of purchase, unlike Botox and Dysport, which do.
Does Xeomin need to be refrigerated?
The answer to this question is no, Xeomin does not need to be refrigerated before reconstitution. Due to its unique formulation, Xeomin is inherently stable at room temperature. This is because Xeomin contains only the purified form of botulinum toxin type A, without any additional complexing proteins that may require refrigeration, unlike its counterparts.
However, once Xeomin has been reconstituted with sterile saline, it is recommended to be stored in a refrigerator at a temperature between 2-8 degrees Celsius (35-46 degrees Fahrenheit). This is to ensure the stability and effectiveness of the product for a longer period of time. When stored properly, reconstituted Xeomin can be used for up to 24 hours after reconstitution.
Why does reconstituted Xeomin need refrigeration?
Refrigeration of reconstituted Xeomin is necessary to maintain its potency and stability. The refrigeration helps to slow down the degradation process and maintain the quality of the product for a longer duration. Storing Xeomin in a cool environment helps to prevent the breakdown of the neurotoxin and maintain its efficacy.
How should Xeomin be stored?
Before reconstitution, Xeomin should be stored at a controlled room temperature away from direct sunlight and heat sources. The temperature should be between 15-25 degrees Celsius (59-77 degrees Fahrenheit). It is essential to keep Xeomin in its original packaging until it is ready to be used.
Once Xeomin has been reconstituted, it should be stored in a refrigerator between 2-8 degrees Celsius (35-46 degrees Fahrenheit). The product should be protected from light and not be frozen. It is crucial to keep reconstituted Xeomin away from any potential contaminants and ensure that it is used within the recommended time frame of 24 hours.
What happens if Xeomin is not refrigerated?
If Xeomin is not refrigerated after reconstitution, its potency may decrease over time. The lack of refrigeration can lead to the breakdown of the neurotoxin, rendering it less effective. It is important to follow the recommended storage guidelines to ensure that Xeomin remains stable and maintains its desired results.
Can Xeomin be transported without refrigeration?
Xeomin can be transported without refrigeration if it is in its unopened, original packaging. The product is stable at room temperature for a certain period. However, it is advisable to minimize exposure to extreme temperatures and ensure that the product is refrigerated as soon as possible upon arrival at its final destination.
When it comes to transporting reconstituted Xeomin, refrigeration is necessary. It is essential to use insulated packaging and cold packs to maintain the appropriate storage temperature during transportation to prevent any degradation of the product.
Consult with your healthcare professional
It is crucial to consult with your healthcare professional, such as a dermatologist or plastic surgeon, for guidance on the storage and handling of Xeomin. They will provide you with specific instructions tailored to your needs and ensure that you are following the correct protocols.
In conclusion, while Xeomin does not need to be refrigerated before reconstitution, it is essential to refrigerate it after reconstitution to maintain its stability and effectiveness. Proper storage, following refrigeration guidelines, and using reconstituted Xeomin within the recommended time frame are crucial for optimal results. Consulting with a healthcare professional will provide you with the necessary guidance for the storage and handling of Xeomin to ensure a successful and safe treatment.