Benlysta, a medication used for treating systemic lupus erythematosus (SLE), is a biologic drug that requires proper storage to ensure its effectiveness and safety. One of the common concerns regarding this medication is how long it can be out of the refrigerator without compromising its quality. In this article, we will delve into the important storage guidelines for Benlysta and shed light on how to maintain its potency.
Understanding Benlysta and Its Storage Requirements
Benlysta, also known by its generic name belimumab, is a medication that belongs to a group of drugs called monoclonal antibodies. It is primarily used to treat adults with active SLE who require additional therapy despite standard treatment options. As a biologic drug, Benlysta is made from living organisms and is highly sensitive to external factors, including temperature.
The Importance of Proper Storage
Maintaining proper storage conditions for Benlysta is crucial to ensure that it remains effective and safe for use. Improper storage, such as exposing the medication to extreme temperatures, can lead to degradation and loss of potency. Consequently, patients may not receive the full therapeutic benefit of the drug, compromising their treatment outcomes.
Storage Guidelines for Benlysta
To maximize the shelf life and maintain the potency of Benlysta, it is essential to adhere to the storage guidelines provided. These guidelines are aimed at protecting the medication from temperature fluctuations that could impact its stability. Here are the important storage recommendations for Benlysta:
Refrigeration
Benlysta should be stored in the refrigerator between temperatures of 2°C to 8°C (36°F to 46°F). The medication should be kept in its original packaging to protect it from light. It is crucial to avoid freezing Benlysta, as this can cause irreversible damage to the drug. Freezing the medication may result in the formation of ice crystals, altering its composition and rendering it ineffective.
Out-of-Refrigerator Period
While it is recommended to store Benlysta in the refrigerator, the medication can be kept at room temperature for a brief period if necessary. According to the manufacturer’s guidelines, Benlysta can be left out of refrigeration for up to 12 hours. However, it is essential to note that this out-of-refrigerator time should be limited, and any unused medication should be discarded after this period.
Returning to Refrigeration
Once Benlysta has been taken out of the refrigerator, it should be placed back in the refrigerator as soon as possible. Storing the medication at room temperature for an extended duration can compromise its stability and render it ineffective. It is crucial to ensure that Benlysta is kept away from sources of heat and direct sunlight during this out-of-refrigerator period.
Travel and Non-Refrigerated Storage
In certain situations, such as travel, patients may find themselves unable to refrigerate Benlysta for an extended period. The medication can be stored at controlled room temperature, not to exceed 25°C (77°F), for a maximum of 14 days. However, it is recommended to return the medication to refrigeration as soon as possible. If storing at room temperature exceeds 14 days or temperatures rise above 25°C (77°F), the medication should be discarded.
Consult Your Healthcare Provider
While the storage guidelines mentioned above offer general recommendations for storing Benlysta, it is essential to consult your healthcare provider for specific instructions based on your unique circumstances. They may provide you with additional guidance based on factors such as the temperature conditions in your area or any specific storage requirements for your medication batch.
Monitoring Temperature
Monitoring the temperature of your refrigerator is another important aspect of medication storage. A reliable refrigerator thermometer can help ensure that the temperature remains within the recommended range of 2°C to 8°C (36°F to 46°F). If you suspect that the refrigerator has been operating outside of this range for an extended period, it is crucial to consult your healthcare provider or pharmacist for guidance on the usability of the medication.
Discarding Expired or Improperly Stored Medication
It is critical to only use Benlysta that has been stored according to the guidelines and has not expired. Expired or improperly stored medication should be discarded appropriately. Your healthcare provider or pharmacist can provide you with instructions on how to dispose of the medication properly.
Conclusion
Proper storage of Benlysta is essential to maintain its potency and ensure the best possible therapeutic outcomes for individuals with SLE. Adhering to the recommended storage guidelines, including refrigeration and limited out-of-refrigerator periods, can help preserve the effectiveness of the medication. Consulting your healthcare provider for personalized instructions and diligently monitoring the storage conditions can further enhance the safety and efficacy of Benlysta. By following these guidelines, patients can optimize their treatment experience with Benlysta and enhance their overall well-being.