Aimovig and Storage: What Happens If It Is Not Refrigerated?
Aimovig, also known as erenumab-aooe, is a prescribed medication used for the prevention of migraines in adults. It belongs to a class of drugs called calcitonin gene-related peptide (CGRP) inhibitors. Aimovig is self-injected once a month and has shown effectiveness in reducing the frequency and severity of migraines for many patients. However, it is crucial to store Aimovig properly to maintain its efficacy and safety. In this article, we will explore the importance of refrigeration for Aimovig and what happens if it is not stored at the recommended temperature.
The Importance of Proper Storage
Why does Aimovig need to be refrigerated?
Aimovig is a biologic drug that contains sensitive active ingredients. Like many other biologic drugs, Aimovig requires refrigeration to maintain its potency and stability. When stored within the recommended temperature range of 36°F to 46°F (2°C to 8°C), Aimovig can retain its effectiveness and remain safe for use.
What happens if Aimovig is not refrigerated?
If Aimovig is not refrigerated as instructed, its efficacy may be compromised. The active ingredients in the medication can degrade when exposed to temperatures outside the recommended range. This degradation can result in a decrease in its effectiveness, making it less able to prevent migraines as intended.
Furthermore, if Aimovig is not refrigerated, it may lead to the growth of harmful bacteria or spoilage of the medication. Using Aimovig that has been compromised in any way can potentially be unsafe and may cause adverse effects or an ineffective treatment outcome.
How long can Aimovig be stored outside the refrigerator?
Aimovig can be stored at room temperature (up to 77°F or 25°C) for a maximum of 7 days. This is only applicable to the autoinjector and prefilled syringe. If the medication remains at room temperature for more than 7 days, it should be discarded and not used.
It is important to note that Aimovig should never be frozen. Freezing can damage the medication and render it ineffective. If Aimovig accidentally freezes, it should be discarded immediately, and a new dose should be obtained.
Proper Storage and Handling Guidelines
Refrigerating Aimovig
To ensure the effectiveness and safety of Aimovig, it should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). During storage, Aimovig should be kept in its original packaging to protect it from light. Ensure the medication is not placed directly against the cooling element of the refrigerator, as it may freeze and become unusable.
It is essential to avoid storing Aimovig near the freezer compartment, where it may be exposed to very low temperatures. The refrigerator door, although convenient, may experience more temperature variations due to frequent opening and closing. Therefore, it is preferable to store the medication in the main body of the refrigerator, where the temperature remains more consistent.
Transporting Aimovig
When transporting Aimovig, it is essential to maintain the appropriate storage conditions. Aimovig can be stored at controlled room temperature (up to 77°F or 25°C) for a maximum of 24 hours. Beyond this time frame, it should be discarded.
During transportation, it is best to keep Aimovig in an insulated bag or cooler with ice packs to maintain a low temperature. This will help prevent exposure to excessive heat or freezing temperatures outside of the recommended range.
Protecting Aimovig from Light
Like many other medications, Aimovig is sensitive to light. It is recommended to keep Aimovig in its original packaging, which is designed to protect it from light exposure. If the packaging is opened, it is recommended to wrap the medication in aluminum foil or store it in a light-blocking container to minimize light exposure.
Other Considerations
Always check the expiration date on the packaging of Aimovig before using it. Expired medication may not be effective and should be discarded.
If Aimovig appears discolored, contains particles, or has been improperly stored, it should not be used. Discard any unused or expired Aimovig as directed by your healthcare provider or local regulations.
It is vital to keep Aimovig and any medication out of the reach of children and pets. Store the medication in a secure place to prevent accidental misuse or ingestion.
In Conclusion
Proper storage of Aimovig, including refrigeration within the recommended temperature range, is essential to maintain its efficacy and safety. Deviating from the storage guidelines can compromise the medication and potentially lead to ineffective treatment or adverse effects. Always follow the instructions provided by your healthcare provider and the manufacturer to ensure the optimal benefit of Aimovig in preventing migraines. By prioritizing proper storage and handling, you can maximize the potential benefits of this medication and improve your quality of life.