Does Excede Need to be Refrigerated? The Truth Revealed

The Truth Revealed: Does Excede Need to be Refrigerated?

Excede is an antibiotic medication commonly used in veterinary medicine for the treatment of respiratory and soft tissue infections in horses and cattle. When it comes to storing and handling medications, there are often specific instructions that need to be followed to ensure their effectiveness and safety. One question that frequently arises among pet owners and veterinarians is whether Excede needs to be refrigerated. In this article, we will delve into the details and shed light on the truth behind Excede’s refrigeration requirements.

The Importance of Proper Medication Storage

Proper storage of medications is crucial to maintain their potency and effectiveness. Improper storage can lead to the degradation of active ingredients, rendering them ineffective or even harmful. Temperature, light exposure, and humidity are factors that can significantly impact the stability of medications.

Understanding Excede

Excede contains an active ingredient called ceftiofur crystalline-free acid, which belongs to the class of cephalosporin antibiotics. This medication is formulated to provide a sustained therapeutic effect, eliminating the need for frequent dosing.

Manufacturer’s Recommendations

To determine whether Excede needs to be refrigerated, it’s essential to refer to the manufacturer’s recommendations. The package insert and labeling provide valuable information regarding storage instructions. According to Zoetis, the manufacturer of Excede, the product does not require refrigeration when stored in the original unopened container.

However, once the seal of the container is broken, the manufacturer advises using the product within 28 days if stored at room temperature (up to 25°C/77°F). It is important to note that these recommendations may vary between different formulations and countries, so always consult the specific product information or your veterinarian for accurate guidance.

Factors to Consider

While refrigeration is not necessary for the unopened Excede, several factors should be taken into account to ensure its stability and effectiveness.

Temperature

Temperature plays a crucial role in maintaining medication stability. Excede is formulated to be stable at room temperature for up to 28 days after the seal is broken. However, it is important to avoid exposing Excede to excessive heat or cold. Extreme temperatures can cause deterioration of the active ingredient, potentially reducing its efficacy. Therefore, it is advisable to store opened containers of Excede in a cool and dry place, away from direct sunlight.

Contamination

Another vital aspect to consider is the risk of contamination. It is crucial to handle Excede with care to prevent the introduction of bacteria or foreign substances that can compromise the medication’s quality. Always ensure clean hands and clean surfaces when preparing or administering Excede. Additionally, avoid touching the tip of the syringe or any other contaminants that may come in contact with the medication.

Avoid Freezing

Although refrigeration is not required, freezing Excede should be strictly avoided. Freezing can cause structural changes in the medication, leading to decreased potency or potential damage to the active ingredient. If Excede accidentally freezes, it should not be used, and proper disposal methods should be followed in consultation with a veterinarian.

Consult Your Veterinarian

While information regarding the storage and handling of Excede is essential, it is always recommended to consult your veterinarian for specific guidance. Veterinarians are well-versed in the proper administration and storage practices for medications, including Excede. Each animal and situation may have unique considerations, and your veterinarian can provide tailored advice based on your pet’s specific needs.

In Conclusion

In conclusion, Excede does not require refrigeration when stored in an unopened container. However, once the seal is broken, it is advised to use the product within 28 days if stored at room temperature. It is crucial to store Excede away from extreme temperatures, avoid freezing, and maintain proper hygiene practices during preparation and administration. To ensure the safety and efficacy of Excede or any medication, always consult your veterinarian for guidance specific to your pet’s needs. By following the manufacturer’s recommendations and seeking professional advice, you can confidently and effectively utilize Excede for the treatment of respiratory and soft tissue infections in your beloved animals.

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